iTWire - $3m federal government grant supports ‘world-first’ IVF study
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Friday, 08 December 2023 13:26
$3m federal government grant supports ‘world-first’ IVF study Featured
By Gordon Peters
The Federal Government has allocated a $3 million grant to researchers to support a world-first IVF study on how whole genome sequencing can be used to achieve better patient outcomes with IVF medications.
Researchers from Virtus Health, healthtech startup 23Strands and Monash University, will receive the funding over four years from the government’s Medical Research Future Fund (MRFF).
James Pyne, Virtus Health CEO said: “The impact of this grant has huge potential to benefit all IVF patients and is a significant step forward for IVF research and innovation.
“Having a better understanding of a patient’s genomic sequencing can help clinicians deliver improved fertility insights, treatments, and personalised medicine, and ultimately better success rates.”
Lead researcher Professor Beverley Vollenhoven from Monash University says the study has the potential to revolutionise the entire landscape of fertility care. “The groundbreaking collaboration of integrating genomics, artificial intelligence and clinical care aspires to set a new global standard to positively improve women’s responses to IVF medications.”
The researers say that by understanding how a woman’s genes can affect how they respond to IVF medications, the study’s end goal is to create an AI-driven tool to deliver better targeted doses and improve IVF success rates.
A recent pilot study by Virtus Health and 23Strands found genetic variations mean every woman has a different response to ovarian stimulation medication.
The MRFF grant will enable the research team to build on these preliminary findings; and conduct a four-year randomised control trial (RCT); the gold standard and most scientifically rigorous assessment method, to help develop a tool for personally targeted dosing of medications.
23Strands co-founder and CEO Mark Grosser said, “This world-first project is special because we will be using new ways to process information about IVF treatments. 23Strands brings innovation that combines data from scientific research, medical records and genetics to deliver tailo tailored personalised medical reports for women. Our world-leading partners will help ensure that this is done in an ethical, safe and effective way.”
A/Prof Vinayak Smith, Head of New Ventures at Virtus Health said: “Virtus Health was the first to develop artificial intelligent embryo selection software. With this new study, we aim to be the first IVF service provider in Australia to offer whole-genome sequencing and AI to augment reproductive decision making and help people achieve their dream of starting a family.”
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