U.S. stocks fell Thursday to cap another losing week on Wall Street as investors digested a flurry of bank earnings and reeled from more red-hot CPI numbers.

The S&P 500 and tech-heavy Nasdaq Composite each settled at four-week lows, recording declines of 1.2% and 2.2%, respectively. The Dow Jones Industrial Average retreated from a slight advance earlier in the session to close 0.3% lower. Meanwhile, Treasury yields climbed higher, with the 10-year benchmark marking its biggest one-week jump to hit 2.8%, the highest level since December 2018.

The majority of U.S. market indexes finished lower for the second straight week as war in Eastern Europe, inflationary pressures and anticipation for more combative measures by the Federal Reserve to tame rising price levels continued to weigh on sentiment.

“There’s a lot of fear and anticipation as we’re moving into this period of higher interest rates,” Portia Capital Management owner and president Michelle Connell told Yahoo Finance Live. “We’re just not quite sure how much the Fed’s going to dial those up. There’s a lot of uncertainty.”

Social media giant Twitter (TWTR) was again in focus on Thursday after Tesla CEO Elon Musk offered to buy the platform for $54.20 per share, or about $41 billion in cash. In a bid for the company outlined in a new SEC filing, Musk said Twitter must go private in order to make effective changes. Shares of Twitter were down 1.5% to $45.18 a piece at Thursday's close.

Investors digested quarterly results from banking heavyweights Wells Fargo (WFC), Goldman Sachs (GS), Morgan Stanley (MS), and Citigroup (C) that reflected a lackluster start to 2022, with profits mostly down across the board after a boom year for the industry last year when it benefited from record dealmaking activity and a financial boost from releasing reserves set aside for potential pandemic loan losses.

The initial batch of reports preface a milder quarter for earnings growth than previous periods. However, earnings are expected to be a bright spot for investors who much of this year so far have grappled with sharp market swings tied to worsening geopolitical risk, inflationary pressures and fears monetary tightening may prompt an economic contraction as the Federal Reserve sets out on its rate hiking plans.