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Researchers bypass optic nerve, deliver images directly to blind woman's brain |...

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Researchers bypass optic nerve, deliver images directly to blind woman's brain

Brain implant allows patient to see shapes, letters after more than 16 years of blindness

By Jimmy Pezzone October 31, 2021, 7:17 AM 40 comments
Researchers bypass optic nerve, deliver images directly to blind woman's brain

Through the looking glass: A Spanish woman lost her vision due to a rapidly progressing condition affecting her optic nerves. With the help of researchers and a small electrode implanted in her visual cortex, she has taken the first steps toward restoring her vision... without using her eyes.

Berna Gomez's world was turned upside down when she was diagnosed with toxic optic neuropathy at age 42. The rapidly progressing disease deteriorated the Spanish science teacher's optic nerves and rendered her blind in a matter of days. Thanks to researchers from the University of Utah and Miguel Hernandez University in Spain, Gomez may now have a chance at restoring her functional vision.

The breakthrough was achieved using an implant known as the Moran|Cortivis Prosthesis. The device, which consists of 96 individual electrodes, is implanted directly in the patient's visual cortex. Once in place, the implant's electrodes can be stimulated in specific combinations to deliver "images" directly to the patient's mind.

According to the Journal of Clinical Investigation, the implant has successfully presented images ranging from spots of light and horizontal lines to some uppercase and lowercase letters.

2021-10-30-image-7.jpg

The achievement is a huge step forward in the quest to restore vision. Unlike retinal implants, this specific advancement completely bypasses the recipient's optic nerve and delivers information directly to the brain's vision center. This direct stimulation provides the potential to deliver images to patients despite any conditions preventing their optic nerve from communicating with their brain.

The silicon-based microelectrode, known as the Utah Electrode Array, is not new technology. The roughly 4mm device's history stretches as far back as 2006, where it was the subject of a Defense Advanced Research Projects Agency (DARPA) collaboration with University of Utah researchers.

The study focused on developing and evaluating a peripheral nerve interface that would allow artificial limbs to move using only thought. In 2019 the University's biomedical engineering team successfully used the array in conjunction with a prosthetic arm to provide a patient with "feeling" via an artificial limb.

Image credit: Human brain from Robina Weermeijer, Berna Gomez from Moran Eye Center

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October 31, 2021 7:55 AMDimitriidDimitriid

The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
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October 31, 2021 10:58 AMRudyBobRudyBob

The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
Those are good questions
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October 31, 2021 11:56 AMUncle AlUncle Al

The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
The human brain has unlimited capability to grasp complex ideas and concepts much like an infants brain grasps the idea's of light, dark, images, etc. While it would probably take somewhat longer, it certainly would not be any longer than a new born. Regardless of all that, this is certainly a very significant advancement in medicine and the use of other means to enhance it!
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October 31, 2021 1:23 PMBullwinkle M

The human brain has unlimited capability to grasp complex ideas and concepts
Who's brain are you referring to ?

Obviously not Alec Baldwin's ?

Try pumping NRA gun safety ad's directly into his brain and watch it short circuit
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October 31, 2021 2:19 PMVomit

VR, private porn viewing, augmented reality. all a very long way off but possible?

October 31, 2021 2:39 PMp51d007p51d007

Every year I get an eye check. I've been going to the same place for decades.
Every time the doc comes in, I ask him if the bionic eye is ready. He laughs, says
no, and I say they must still be having trouble making that boop boop boop sound
like it did on the TV show.

October 31, 2021 2:54 PMcliffordcooleycliffordcooley

Obviously not Alec Baldwin's ?
Try pumping NRA gun safety ad's directly into his brain and watch it short circuit
Alec may be the one that pulled a killing trigger. But he is not the only one to blame. I'm also willing to bet the same could have happened to any of us. Long periods without incidents and safety grows lax for all of us. Especially for people living in the fast lane. This is not a Alec Baldwin problem. It is a problem on a much larger scale. If you want to address the issue. Pointing a finger solely at Alec Baldwin is a cheap shot at denying the true problem.
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October 31, 2021 3:03 PMTrapped Nowhere

How'd we go from blindness to guns
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October 31, 2021 3:36 PMbviktor

Who's brain are you referring to ?

Obviously not Alec Baldwin's ?

Try pumping NRA gun safety ad's directly into his brain and watch it short circuit
What does Baldwin have to do with anything? He was told there's no live bullet in the gun, and he practiced pulling and shooting the gun, that he was supposed to do on scene afterwards.
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October 31, 2021 3:50 PMpcnthuziastpcnthuziast

Off topic, but I'll play. Alec will receive judgement from the creator for murder. Period. So will whoever was directly responsible for loading the gun with live rounds. Gun safety on set should extend to precisely this: The one pulling the trigger should have enough knowledge of firearms and their use that just prior to firing the shot, they themselves should remove the cartridge and inspect the rounds and have the knowledge to be aware of exactly every detail of them including, but not limited to, whether or not they are live. Period.

Guns aren't toys or props. They are weapons designed to end life. Period.

October 31, 2021 4:13 PMBullwinkle M

What does Baldwin have to do with anything? He was told there's no live bullet in the gun, and he practiced pulling and shooting the gun, that he was supposed to do on scene afterwards.
It is irrelevant if he was told the gun was Cold
You MUST treat every gun as if it were Hot!

Rules are already in place to prevent the killing which Baldwin ignored

Baldwin ignored those rules and now wants to implement more rules to prevent such a disaster on everyone else except himself because he will ignore any new rules as well

You do not point a gun at the camera crew (Cold or Hot) and you certainly would never pull the trigger unless you are Alex Baldwin

You do not have 1 homicide among 3 misfires and then call it 1 in a Trillion chance unless you are Alex Baldwin

Well, at least he's not a quitter
Baldwin finally found that Bloody Red October he's been searching for

October 31, 2021 4:32 PMDimitriidDimitriid

Rules are already in place to prevent the killing which Baldwin ignored
You know, I keep hearing this argument and don't worry: I'm not about to pass judgement on Baldwin for good or ill.

But we wouldn't even need any rules at all if we didn't have actual guns capable of loading actual ammunition when all you need is a prop with a blocked off barrel and blocked off bullet loading mechanism.

In the past I know practical effects were useful but if we can release like 5 hours of Thanos we can probably afford to use a tiny bit of CGI to add a muscle flash. Even kids on youtube with toys are capable of just using photoshop effects in that look convincing enough with a tiny bit of clever angles and editing, yet these arguments from gun enthusiasts about how incredibly safe guns as prop can be if you follow the protocols yet I never see an argument as to why do you even need an actual gun and not just a blocked off, functionally useless piece of metal instead.
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October 31, 2021 4:40 PMArbieArbie

How'd we go from blindness to guns
I was gonna deflect into the Election Steal Big Lie, but am outclassed before I even got started.

Since this has not already been answered: Can she play Crysis?
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October 31, 2021 4:44 PMBullwinkle M

Can she play Crysis?
LoL
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October 31, 2021 4:58 PMBullwinkle M

But we wouldn't even need any rules at all if we didn't have actual guns capable of loading actual ammunition when all you need is a prop with a blocked off barrel and blocked off bullet loading mechanism.
The only rules you need are......
Any time a real gun is used, you must hire a "Professional Actor", not Alec Baldwin
Same with the crew!

But it was a low budget production and everything was rushed

The professional crew walked off the set because of the many problems being overlooked at the time, and now being denied by management

[link]

October 31, 2021 5:16 PMBullwinkle M

Alec may be the one that pulled a killing trigger. But he is not the only one to blame. I'm also willing to bet the same could have happened to any of us. Long periods without incidents and safety grows lax for all of us. Especially for people living in the fast lane. This is not a Alec Baldwin problem. It is a problem on a much larger scale. If you want to address the issue. Pointing a finger solely at Alec Baldwin is a cheap shot at denying the true problem.
No, it could not happen to any of us

Some people "JOIN THE NRA" and learn gun safety

The true problem is Alec Baldwin and people like him

GUNS DON'T KILL PEOPLE
ALEC BALDWIN DOES!

October 31, 2021 5:24 PMDimitriidDimitriid

The only rules you need are......
Any time a real gun is used...
Yeah no: that does not answers my question. There is no need for a real gun at all. "Small budget" isn't an issue precisely because of my example: kids with nothing but a laptop and an iphone can do prop guns convincingly with something like a bb gun or a well painted piece of wood by just being clever about the shots and photoshopping in a muscle flash and such.

The fact that there's so much tangents and whataboutism about this issue makes me feel like most people foreign to America feel when talking to Americans about guns: You all act and talk like weird, obsessed mini golums when talking about guns.
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October 31, 2021 5:25 PMcliffordcooleycliffordcooley

Some people "JOIN THE NRA" and learn gun safety
And your job is not working with props all day long either is it? It's easy to cast stones when we know nothing of the situation or the people involved.

Are we going to get back to this amazing article? Or are we going to continue bashing someone because a large group had a very bad day?
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October 31, 2021 5:51 PMBullwinkle M

It's easy to cast stones when we know nothing of the situation or the people involved.
We know all that we need to

The situation was rushed and the people involved were incompetent

October 31, 2021 5:55 PMBullwinkle M

Yeah no: that does not answers my question. There is no need for a real gun at all.
No, there was no need for real guns on a rushed low budget set without professional actors or crew

None at all

An unprofessional actor who has no training in weapons and is actively opposed to people owning guns should never be allowed to handle one on a set

October 31, 2021 5:59 PMDimitriidDimitriid

No, there was no need for real guns on a rushed low budget set without professional actors or crew

None at all
By my count, the higher the budget the less of a need for real guns there is anyway. But I feel this partial concede you show is as far as we're going to get so I'll leave it at that.

October 31, 2021 6:01 PMBullwinkle M

By my count, the higher the budget the less of a need for real guns there is anyway. But I feel this partial concede you show is as far as we're going to get so I'll leave it at that.
Smart move

Those who do not have the proper training should never tell a professional what they should do

October 31, 2021 6:03 PMMr Majestyk

The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
Deep learning organic style. Our brain hardwires circuits as we absorb information be it from any senses. 40% of brains processing is required for image processing. We should start with the brain of newborn infants and see how quickly neuronal circuits/synapses are growing/connecting as it vision develops.
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November 1, 2021 8:16 AMDimitriidDimitriid

Deep learning organic style. Our brain hardwires circuits as we absorb information be it from any senses. 40% of brains processing is required for image processing. We should start with the brain of newborn infants and see how quickly neuronal circuits/synapses are growing/connecting as it vision develops.
That's what I alluded to by "learning everything" but while thinking about this it dawn on me that beyond some of the more obvious autonomous functions like breathing, there's some that we've observed to be bypassing cognitive functions like moving your hand away from a fire or jumping out of the way or things that might look like dangerous creatures like snakes or big spiders or overall being startled.

From my extremely amateur recollection of it, those work as an in between: we learn to be fearful of certain things like spiders from our parents but once we "learn" that part it gets wired into a part of the brain that doesn't actually waits for the conscious part of the mind to process the information: we get startled and even if we learn to control it, there's the effects of adrenaline and the flight-or-fight response.

So while we "learn" what the visual information is there's certainly a lot of it that no longer operates by the normal channels of the brain so in theory, bypassing the learning and stimulating that process directly could allow a blind person not just to see but even if the image can't be processed or have no context, to respond accordingly to danger while still being technically blind assuming this process from the OP was partially successful only.

November 1, 2021 9:57 AMwiyosayawiyosaya

The interesting part is looking at how she processes the signal and then compare it to how would a person who was born blind: they would have no concept or reference of what an image even is so how would the information be processed by them? Would their brain would just interpret this as something completely and utterly different meaning we just "learn" everything or would simulating the same parts of the brain would end up producing somewhat similar results so not being able to "see" but being able to process information on an instinctual level like get away out of the path of moving objects and such? Or just somewhere in between even.
FWIW - Interestingly enough, to the best of my knowledge, the mind dreams with images - even in those born blind. [link] What that says to your questions, I am not sure, however, to me, it suggests that the mind has an innate ability to process visual imagery.

I am willing to bet that those working on the tech have done some sort modeling on how the brain processes images, in fact, it would not surprise me if they have extensive fMRI scans of the parts of the brain that are responsible for processing image data. So, instead of relying on the brain having to reformulate its visual model for this device, it would not surprise me if they tried to make this device fit the model that the brain uses by default.

In fact, there has been reasonably successful research into recording the images seen by the brain while dreaming. [link]
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November 1, 2021 9:59 AMwiyosayawiyosaya

Alec may be the one that pulled a killing trigger. But he is not the only one to blame. I'm also willing to bet the same could have happened to any of us. Long periods without incidents and safety grows lax for all of us. Especially for people living in the fast lane. This is not a Alec Baldwin problem. It is a problem on a much larger scale. If you want to address the issue. Pointing a finger solely at Alec Baldwin is a cheap shot at denying the true problem.
This. If I were able upvote you a million times for this comment, I would.

November 1, 2021 10:01 AMwiyosayawiyosaya

No, it could not happen to any of us

Some people "JOIN THE NRA" and learn gun safety

The true problem is Alec Baldwin and people like him

GUNS DON'T KILL PEOPLE
ALEC BALDWIN DOES!
I am sorry to disagree, however, I see comments like this are the true problem. Not people in the movie business that are told their prop guns are safe to fire.

November 1, 2021 10:06 AMwiyosayawiyosaya

We know all that we need to

The situation was rushed and the people involved were incompetent
Ah, so contradicting your original argument. Perfect, buh, buh, buh buhtism.

November 1, 2021 10:14 AMDimitriidDimitriid

FWIW - Interestingly enough, to the best of my knowledge, the mind dreams with images - even in those born blind. [link] What that says to your questions, I am not sure, however, to me, it suggests that the mind has an innate ability to process visual imagery.

I am willing to bet that those working on the tech have done some sort modeling on how the brain processes images, in fact, it would not surprise me if they have extensive fMRI scans of the parts of the brain that are responsible for processing image data. So, instead of relying on the brain having to reformulate its visual model for this device, it would not surprise me if they tried to make this device fit the model that the brain uses by default.

In fact, there has been reasonably successful research into recording the images seen by the brain while dreaming. [link]
Fascinating.

Makes sense now thinking about it since we developed functioning eyes, at least in some fashion, way before we developed cognitive capabilities so it makes sense that there is no need to bypass processing images since that came later during our evolution.

It might even represent a unique challenge or way to solve challenges when it comes to getting closer to true AI.

November 1, 2021 11:18 AMBullwinkle M

This. If I were able upvote you a million times for this comment, I would.
Upvoting a Trillion times would still not make it true

November 1, 2021 11:21 AMBullwinkle M

I am sorry to disagree, however, I see comments like this are the true problem. Not people in the movie business that are told their prop guns are safe to fire.
So then, you would be OK if I shoot and kill you as long as somebody tells me that my gun isn't loaded?

Wow.......Just........WoW

November 1, 2021 1:25 PMcliffordcooleycliffordcooley

So then, you would be OK if I shoot and kill you as long as somebody tells me that my gun isn't loaded?
That is not what any of us are saying. We do however realize accidents happen. And charging people with intent when accidents happen will never solve anything.

The people that brought live rounds to work and lost track of (or intentionally planted) them are the only ones truly guilty. They are the ones that created this rippling effect that no one was anticipating.

You don't blame a kid for playing with his toys when one day one of them goes off. You find out where the toy came from and why it went off. Because to the best of your knowledge they were all safe. Because lets not kid ourselves that is exactly what props are. They are toys. Even though the gun was real. It was still labeled as a prop and used as a toy.

November 1, 2021 2:10 PMBullwinkle M

That is not what any of us are saying. We do however realize accidents happen. And charging people with intent when accidents happen will never solve anything.

The people that brought live rounds to work and lost track of (or intentionally planted) them are the only ones truly guilty. They are the ones that created this rippling effect that no one was anticipating.

You don't blame a kid for playing with his toys when one day one of them goes off. You find out where the toy came from and why it went off. Because to the best of your knowledge they were all safe. Because lets not kid ourselves that is exactly what props are. They are toys. Even though the gun was real. It was still labeled as a prop and used as a toy.
You must be confusing intent with incompetence

Baldwin may not have had intent, but he was totally incompetent

For normal people, you never point "ANY" gun at a person unless your intent is to shoot them

If Baldwin did not understand this fact, he was "TOTALLY" incompetent and should never have been allowed near any gun (EVER)

And simply calling it a prop does not make it a toy
------------------------------------------------------------------
A rock will never understand how dumb the rock is

I could explain it another 100 times, but the rock doesn't "get it"

November 1, 2021 7:27 PMcliffordcooleycliffordcooley

Baldwin may not have had intent, but he was totally incompetent
There was plenty of that to go around for everyone involved. You are intentionally singling out Baldwin. That is wrong and you know it. They were not on a firing range with the intent to use live ammo. They were on a production set with the intent to use props. The only reason I started this back and forth with you. Was because you were completely ignoring everyone else's part in this blame game.
I could explain it another 100 times, but the rock doesn't "get it"
In this case the rock doesn't get it and calls others the rock.

Why are you hung up on Baldwin? Why is his story more important to you that blind people being able to see again?

November 1, 2021 8:54 PMBullwinkle M

Let it go

You are wrong and you know it

Think of the blind who can now see
Not the blind who refuse to see

November 1, 2021 9:09 PMcliffordcooleycliffordcooley

Let it go

You are wrong and you know it

Think of the blind who can now see
Not the blind who refuse to see
Right back at you.

November 2, 2021 12:57 AMcliffordcooleycliffordcooley

Na Uh.....
No, You're a Rock!
I'm leaving this juvenile conversation.

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