ORF1ab ORF1a polyprotein;ORF1ab polyprotein [SARS coronavirus Tor2] - Gene - NCB...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

1. NC_004718.3 Reference assembly

   Range 265..21485 Download GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. NP_828849.7 ORF1ab polyprotein [SARS coronavirus Tor2]

   Status: PROVISIONAL

2. NP_828860.2 nsp1

   Conserved Domains (1) summary pfam11501
   Location:13 → 127 Nsp1; Non structural protein Nsp1

3. NP_828861.2 nsp2

4. NP_828862.2 nsp3

   Conserved Domains (6) summary pfam11633
   Location:509 → 651 SUD-M; Single-stranded poly(A) binding domain pfam01661
   Location:218 → 325 Macro; Macro domain pfam08715
   Location:723 → 1040 Viral_protease; Papain like viral protease pfam12124
   Location:655 → 720 Nsp3_PL2pro; Coronavirus polyprotein cleavage domain pfam12379
   Location:103 → 171 DUF3655; Protein of unknown function (DUF3655) pfam16251
   Location:1066 → 1178 NAR; Nucleic acid-binding domain (NAR)

5. NP_904322.1 nsp4

   Conserved Domains (1) summary pfam16348
   Location:406 → 498 Corona_NSP4_C; Coronavirus nonstructural protein 4 C-terminus

6. NP_828863.1 3C-like protease

   Conserved Domains (1) summary pfam05409
   Location:29 → 306 Peptidase_C30; Coronavirus endopeptidase C30

7. NP_828864.1 nsp6

8. NP_828865.1 nsp7

   Conserved Domains (1) summary pfam08716
   Location:1 → 83 nsp7; nsp7 replicase

9. NP_828866.1 nsp8

   Conserved Domains (1) summary pfam08717
   Location:1 → 198 nsp8; nsp8 replicase

10. NP_828867.1 nsp9

    Conserved Domains (1) summary pfam08710
    Location:1 → 113 nsp9; nsp9 replicase

11. NP_828868.1 nsp10

    Conserved Domains (1) summary pfam09401
    Location:12 → 131 NSP10; RNA synthesis protein NSP10

12. YP_009924301.1 RNA-dependent RNA polymerase

13. NP_828870.1 helicase/NTPase

    Conserved Domains (3) summary COG1112
    Location:323 → 592 DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair] cl21455
    Location:277 → 407 P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases cl22977
    Location:443 → 580 UvrD_C_2; UvrD-like helicase C-terminal domain

14. NP_828872.1 endoribonuclease

    Conserved Domains (1) summary pfam06471
    Location:1 → 68 NSP11; NSP11

15. NP_828873.2 2'-O-MTase

    Conserved Domains (1) summary pfam06460
    Location:2 → 297 NSP13; Coronavirus NSP13

16. NP_828871.1 3' to 5' exonuclease

    Conserved Domains (1) summary pfam06471
    Location:3 → 527 NSP11; NSP11

17. YP_009944365.1 ORF1a polyprotein [SARS coronavirus Tor2]

    Status: PROVISIONAL

18. YP_009944366.1 nsp1

19. YP_009944367.1 nsp2

20. YP_009944368.1 nsp3

21. YP_009944369.1 nsp4

22. YP_009944370.1 3C-like protease

23. YP_009944371.1 nsp6

24. YP_009944372.1 nsp7

25. YP_009944373.1 nsp8

26. YP_009944374.1 nsp9

27. YP_009944375.1 nsp10

28. YP_009944376.1 ndp11